Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons

Volatile anesthetics reduce excitatory synaptic transmission by both presynaptic and postsynaptic mechanisms which include inhibition of depolarization-evoked increases in presynaptic Ca(2+) concentration and blockade of postsynaptic excitatory glutamate receptors. The presynaptic sites of action le...

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Detalles Bibliográficos
Autores principales: Osman, Vanessa, Speigel, Iris, Patel, Kishan, Hemmings, Hugh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467020/
https://www.ncbi.nlm.nih.gov/pubmed/37591734
http://dx.doi.org/10.1523/ENEURO.0114-23.2023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467020/
https://www.ncbi.nlm.nih.gov/pubmed/37591734
http://dx.doi.org/10.1523/ENEURO.0114-23.2023

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