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Altered properties of amyloidogenic prion protein in genetic Creutzfeldt–Jakob disease with PRNP V180I mutation in response to pentosan polysulfate

Genetic Creutzfeldt–Jakob disease (gCJD) with V180I prion protein gene (PRNP) mutation shows weaker prion protein (PrP) deposition histologically compared with sporadic CJD, and it is more difficult to detect protease‐resistant prion protein in immunoblotting. However, we previously reported the aut...

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Detalles Bibliográficos
Autores principales: Shijo, Masahiro, Yoshimura, Motoi, Omae, Tsuyoshi, Hashimoto, Go, Mizoguchi, Tadataka, Kuwashiro, Takahiro, Komori, Takashi, Tsuboi, Yoshio, Saito, Tomoko, Nakagawa, Masanori, Itoh, Kyoko, Honda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467033/
https://www.ncbi.nlm.nih.gov/pubmed/37525413
http://dx.doi.org/10.1111/bpa.13197