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AB(5)-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus

Japanese encephalitis virus (JEV) is an enveloped icosahedral capsid virus with a prime neutralizing epitope present in E protein domain III (EDIII). E dimers are rearranged into a five-fold symmetry of icosahedrons. Cholera toxin B (CTB) and heat-labile enterotoxin B (LTB) of AB(5)-type toxin was u...

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Detalles Bibliográficos
Autores principales: Ahn, Jina, Yu, Ji Eun, Kim, Hanna, Sung, Jemin, Han, Gyoonhee, Sohn, Myung Hyun, Seong, Baik-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467048/
https://www.ncbi.nlm.nih.gov/pubmed/37505694
http://dx.doi.org/10.3390/toxins15070425