Emodin, an Emerging Mycotoxin, Induces Endoplasmic Reticulum Stress-Related Hepatotoxicity through IRE1α–XBP1 Axis in HepG2 Cells

Emodin, an emerging mycotoxin, is known to be hepatotoxic, but its mechanism remains unclear. We hypothesized that emodin could induce endoplasmic reticulum (ER) stress through the inositol-requiring enzyme 1 alpha (IRE1α)–X-box-binding protein 1 (XBP1) pathway and apoptosis, which are closely corre...

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Detalles Bibliográficos
Autores principales: Park, Su Been, Cho, Gun Hee, Park, Young Eun, Chun, Hyang Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467057/
https://www.ncbi.nlm.nih.gov/pubmed/37505724
http://dx.doi.org/10.3390/toxins15070455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467057/
https://www.ncbi.nlm.nih.gov/pubmed/37505724
http://dx.doi.org/10.3390/toxins15070455

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