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Domperidone Inhibits Clostridium botulinum C2 Toxin and Bordetella pertussis Toxin

Bordetella pertussis toxin (PT) and Clostridium botulinum C2 toxin are ADP-ribosylating toxins causing severe diseases in humans and animals. They share a common translocation mechanism requiring the cellular chaperones Hsp90 and Hsp70, cyclophilins, and FK506-binding proteins to transport the toxin...

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Detalles Bibliográficos
Autores principales: Jia, Jinfang, Braune-Yan, Maria, Lietz, Stefanie, Wahba, Mary, Pulliainen, Arto T., Barth, Holger, Ernst, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467066/
https://www.ncbi.nlm.nih.gov/pubmed/37505681
http://dx.doi.org/10.3390/toxins15070412