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Of Seven New K(+) Channel Inhibitor Peptides of Centruroides bonito, α-KTx 2.24 Has a Picomolar Affinity for Kv1.2

Seven new peptides denominated CboK1 to CboK7 were isolated from the venom of the Mexican scorpion Centruroides bonito and their primary structures were determined. The molecular weights ranged between 3760.4 Da and 4357.9 Da, containing 32 to 39 amino acid residues with three putative disulfide bri...

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Detalles Bibliográficos
Autores principales: Shakeel, Kashmala, Olamendi-Portugal, Timoteo, Naseem, Muhammad Umair, Becerril, Baltazar, Zamudio, Fernando Z., Delgado-Prudencio, Gustavo, Possani, Lourival Domingos, Panyi, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467108/
https://www.ncbi.nlm.nih.gov/pubmed/37624263
http://dx.doi.org/10.3390/toxins15080506