Cargando…

Dynamics and Molecular Interactions of GPI-Anchored CD59

CD59 is a GPI-anchored cell surface receptor that serves as a gatekeeper to controlling pore formation. It is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. While CD59 blocks MAC pores, the receptor is co-opted by bacter...

Descripción completa

Detalles Bibliográficos
Autores principales: Voisin, Tomas B., Couves, Emma C., Tate, Edward W., Bubeck, Doryen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467114/
https://www.ncbi.nlm.nih.gov/pubmed/37505699
http://dx.doi.org/10.3390/toxins15070430