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Machine Learning with Alpha Toxin Phenotype to Predict Clinical Outcome in Patients with Staphylococcus aureus Bloodstream Infection

Staphylococcus aureus bloodstream (SAB) infection remains a leading cause of sepsis-related mortality. Yet, current treatment does not account for variable virulence traits that mediate host dysregulated immune response, such as SA α-toxin (Hla)-mediated thrombocytopenia. Here, we applied machine le...

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Detalles Bibliográficos
Autores principales: Beadell, Brent, Nehra, Surya, Gusenov, Elizabeth, Huse, Holly, Wong-Beringer, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467129/
https://www.ncbi.nlm.nih.gov/pubmed/37505686
http://dx.doi.org/10.3390/toxins15070417