A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site

A disintegrin and metalloproteinase (ADAM) family proteins are a major class of membrane-anchored multidomain proteinases that are responsible for the shedding of cell surface protein ectodomains, including amyloid precursor protein (APP). Human ADAM 9, 10, and 17 proteolyze APPs and produce non-amy...

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Detalles Bibliográficos
Autores principales: Futai, Eugene, Kawasaki, Hajime, Sato, Shinichi, Daoudi, Khadija, Hidaka, Masafumi, Tomita, Taisuke, Ogawa, Tomohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467146/
https://www.ncbi.nlm.nih.gov/pubmed/37624257
http://dx.doi.org/10.3390/toxins15080500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467146/
https://www.ncbi.nlm.nih.gov/pubmed/37624257
http://dx.doi.org/10.3390/toxins15080500

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