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Evaluation of serum cytokines and acute phase proteins as possible pharmacodynamic biomarkers to monitor endoscopic remission during ustekinumab therapy in patients with Crohn’s disease

BACKGROUND: Since not all Crohn’s disease (CD) patients respond adequately to ustekinumab therapy, biomarkers could aid to monitor treatment response and optimize therapeutic outcomes. OBJECTIVES: To explore the dynamics of serum biomarker concentrations to monitor the response to ustekinumab treatm...

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Detalles Bibliográficos
Autores principales: Van den Berghe, Nathalie, Alsoud, Dahham, Verstockt, Bram, Vermeire, Séverine, Declerck, Paul, Thomas, Debby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467236/
https://www.ncbi.nlm.nih.gov/pubmed/37655059
http://dx.doi.org/10.1177/17562848231189110