SOD1(G93A) Astrocyte-Derived Extracellular Vesicles Induce Motor Neuron Death by a miRNA-155-5p-Mediated Mechanism

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (MN) degeneration. Astrocytes surrounding MNs are known to modulate ALS progression. When cocultured with astrocytes overexpressing the ALS-linked mutant Cu/Zn superoxide dismutase...

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Detalles Bibliográficos
Autores principales: Marton, Soledad, Miquel, Ernesto, Acosta-Rodríguez, Joaquín, Fontenla, Santiago, Libisch, Gabriela, Cassina, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
The Role of Glial Cells in the Nervous System in Health and Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467309/
https://www.ncbi.nlm.nih.gov/pubmed/37644868
http://dx.doi.org/10.1177/17590914231197527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467309/
https://www.ncbi.nlm.nih.gov/pubmed/37644868
http://dx.doi.org/10.1177/17590914231197527

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