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SOD1(G93A) Astrocyte-Derived Extracellular Vesicles Induce Motor Neuron Death by a miRNA-155-5p-Mediated Mechanism
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (MN) degeneration. Astrocytes surrounding MNs are known to modulate ALS progression. When cocultured with astrocytes overexpressing the ALS-linked mutant Cu/Zn superoxide dismutase...
Autores principales: | Marton, Soledad, Miquel, Ernesto, Acosta-Rodríguez, Joaquín, Fontenla, Santiago, Libisch, Gabriela, Cassina, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467309/ https://www.ncbi.nlm.nih.gov/pubmed/37644868 http://dx.doi.org/10.1177/17590914231197527 |
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