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Identification of TMEM53 as a novel SADS-CoV restriction factor that targets viral RNA-dependent RNA polymerase

Zoonotic transmission of coronaviruses (CoVs) poses a serious public health threat. Swine acute diarrhea syndrome coronavirus (SADS-CoV), originating from a bat HKU2-related CoV, causes devastating swine diseases and poses a high risk of spillover to humans. Currently, licensed therapeutics that can...

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Detalles Bibliográficos
Autores principales: Yao, Yu-Lin, Luo, Yun, Wang, Qi, Geng, Rong, Chen, Ying, Liu, Mei-Qin, Li, Bei, Chen, Jing, Wu, Chun-Guang, Jia, Jing-Kun, Luo, Jing-Yi, He, Yan-Tong, Jiang, Ting-Ting, Zhu, Yan, Hu, Ben, Zhou, Peng, Shi, Zheng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467534/
https://www.ncbi.nlm.nih.gov/pubmed/37584551
http://dx.doi.org/10.1080/22221751.2023.2249120