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Whole-genome CpG-resolution DNA Methylation Profiling of HNSCC Reveals Distinct Mechanisms of Carcinogenesis for Fine-scale HPV+ Cancer Subtypes

DNA methylation is a vital early step in carcinogenesis. Most findings of aberrant DNA methylation in head and neck squamous cell carcinomas (HNSCC) are array based with limited coverage and resolution, and mainly explored by human papillomavirus (HPV) status, ignoring the high heterogeneity of this...

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Detalles Bibliográficos
Autores principales: Qin, Tingting, Li, Shiting, Henry, Leanne E., Chou, Elysia, Cavalcante, Raymond G., Garb, Bailey F., D'Silva, Nisha J., Rozek, Laura S., Sartor, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467604/
https://www.ncbi.nlm.nih.gov/pubmed/37654626
http://dx.doi.org/10.1158/2767-9764.CRC-23-0009