Cargando…
Biosynthetic incorporation of fluorinated amino acids into the nonribosomal peptide gramicidin S
Fluorine is a key element in medicinal chemistry, as it can significantly enhance the pharmacological properties of drugs. In this study, we aimed to biosynthetically produce fluorinated analogues of the antimicrobial cyclic decapeptide gramicidin S (GS). However, our results show that the A-domain...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
RSC
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10467612/ https://www.ncbi.nlm.nih.gov/pubmed/37654511 http://dx.doi.org/10.1039/d3cb00061c |