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The shape of cancer relapse: Topological data analysis predicts recurrence in paediatric acute lymphoblastic leukaemia

Although children and adolescents with acute lymphoblastic leukaemia (ALL) have high survival rates, approximately 15-20% of patients relapse. Risk of relapse is routinely estimated at diagnosis by biological factors, including flow cytometry data. This high-dimensional data is typically manually as...

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Detalles Bibliográficos
Autores principales: Chulián, Salvador, Stolz, Bernadette J., Martínez-Rubio, Álvaro, Blázquez Goñi, Cristina, Rodríguez Gutiérrez, Juan F., Caballero Velázquez, Teresa, Molinos Quintana, Águeda, Ramírez Orellana, Manuel, Castillo Robleda, Ana, Fuster Soler, José Luis, Minguela Puras, Alfredo, Martínez Sánchez, María V., Rosa, María, Pérez-García, Víctor M., Byrne, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468039/
https://www.ncbi.nlm.nih.gov/pubmed/37578973
http://dx.doi.org/10.1371/journal.pcbi.1011329