Targeting FoxO proteins induces lytic reactivation of KSHV for treating herpesviral primary effusion lymphoma

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic virus consisting of both latent and lytic life cycles. Primary effusion lymphoma (PEL) is an aggressive B-cell lineage lymphoma, dominantly latently infected by KSHV. The latent infection of KSHV is persistent and poses an obstacle to ki...

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Detalles Bibliográficos
Autores principales: Lan, Jungang, Wang, Yeqing, Yue, Shusheng, Xu, Duo, Li, Yinan, Peng, Xiangyu, Hu, Jiao, Ju, Enguo, He, Shanping, Li, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468091/
https://www.ncbi.nlm.nih.gov/pubmed/37594999
http://dx.doi.org/10.1371/journal.ppat.1011581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468091/
https://www.ncbi.nlm.nih.gov/pubmed/37594999
http://dx.doi.org/10.1371/journal.ppat.1011581

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