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GIRK2 potassium channels expressed by the AgRP neurons decrease adiposity and body weight in mice

It is well known that the neuropeptide Y (NPY)/agouti-related peptide (AgRP) neurons increase appetite and decrease thermogenesis. Previous studies demonstrated that optogenetic and/or chemogenetic manipulations of NPY/AgRP neuronal activity alter food intake and/or energy expenditure (EE). However,...

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Detalles Bibliográficos
Autores principales: Oh, Youjin, Yoo, Eun-Seon, Ju, Sang Hyeon, Kim, Eunha, Lee, Seulgi, Kim, Seyun, Wickman, Kevin, Sohn, Jong-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468093/
https://www.ncbi.nlm.nih.gov/pubmed/37594983
http://dx.doi.org/10.1371/journal.pbio.3002252