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CaMKII autophosphorylation can occur between holoenzymes without subunit exchange

The dodecameric protein kinase CaMKII is expressed throughout the body. The alpha isoform is responsible for synaptic plasticity and participates in memory through its phosphorylation of synaptic proteins. Its elaborate subunit organization and propensity for autophosphorylation allow it to preserve...

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Detalles Bibliográficos
Autores principales: Lučić, Iva, Héluin, Léonie, Jiang, Pin-Lian, Castro Scalise, Alejandro G, Wang, Cong, Franz, Andreas, Heyd, Florian, Wahl, Markus C, Liu, Fan, Plested, Andrew JR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468207/
https://www.ncbi.nlm.nih.gov/pubmed/37566455
http://dx.doi.org/10.7554/eLife.86090