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Using Drosophila to identify naturally occurring genetic modifiers of amyloid beta 42- and tau-induced toxicity
Alzheimer's disease is characterized by 2 pathological proteins, amyloid beta 42 and tau. The majority of Alzheimer's disease cases in the population are sporadic and late-onset Alzheimer's disease, which exhibits high levels of heritability. While several genetic risk factors for lat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468303/ https://www.ncbi.nlm.nih.gov/pubmed/37311212 http://dx.doi.org/10.1093/g3journal/jkad132 |