Cargando…

Using Drosophila to identify naturally occurring genetic modifiers of amyloid beta 42- and tau-induced toxicity

Alzheimer's disease is characterized by 2 pathological proteins, amyloid beta 42 and tau. The majority of Alzheimer's disease cases in the population are sporadic and late-onset Alzheimer's disease, which exhibits high levels of heritability. While several genetic risk factors for lat...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ming, Zinkgraf, Matthew, Fitzgerald-Cook, Cecilia, Harrison, Benjamin R, Putzier, Alexandra, Promislow, Daniel E L, Wang, Adrienne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468303/
https://www.ncbi.nlm.nih.gov/pubmed/37311212
http://dx.doi.org/10.1093/g3journal/jkad132