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Using Drosophila to identify naturally occurring genetic modifiers of amyloid beta 42- and tau-induced toxicity

Alzheimer's disease is characterized by 2 pathological proteins, amyloid beta 42 and tau. The majority of Alzheimer's disease cases in the population are sporadic and late-onset Alzheimer's disease, which exhibits high levels of heritability. While several genetic risk factors for lat...

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Detalles Bibliográficos
Autores principales:	Yang, Ming, Zinkgraf, Matthew, Fitzgerald-Cook, Cecilia, Harrison, Benjamin R, Putzier, Alexandra, Promislow, Daniel E L, Wang, Adrienne M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468303/ https://www.ncbi.nlm.nih.gov/pubmed/37311212 http://dx.doi.org/10.1093/g3journal/jkad132

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