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Aldehyde Dehydrogenase 2 (ALDH2) Genotype Affects Rectal Cancer Susceptibility Due to Alcohol Consumption

Background: Epidemiologic studies have shown the association between alcohol consumption and colorectal cancer, especially for rectal cancer. The alcohol related enzyme encoding gene ALDH2 has polymorphism Glu487Lys, and 487Lys allele is closely linked with phenotypic loss of enzyme activity. Materi...

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Detalles Bibliográficos
Autores principales: Matsuo, Keitaro, Hamajima, Nobuyuki, Hirai, Takashi, Kato, Tomoyuki, Koike, Kouichi, Inoue, Manami, Takezaki, Toshiro, Tajima, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Epidemiological Association 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468342/
https://www.ncbi.nlm.nih.gov/pubmed/12033531
http://dx.doi.org/10.2188/jea.12.70