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Population-based heteropolymer design to mimic protein mixtures
Biological fluids, the most complex blends, have compositions that constantly vary and cannot be molecularly defined(1). Despite these uncertainties, proteins fluctuate, fold, function and evolve as programmed(2–4). We propose that in addition to the known monomeric sequence requirements, protein se...
Autores principales: | Ruan, Zhiyuan, Li, Shuni, Grigoropoulos, Alexandra, Amiri, Hossein, Hilburg, Shayna L., Chen, Haotian, Jayapurna, Ivan, Jiang, Tao, Gu, Zhaoyi, Alexander-Katz, Alfredo, Bustamante, Carlos, Huang, Haiyan, Xu, Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468399/ https://www.ncbi.nlm.nih.gov/pubmed/36890370 http://dx.doi.org/10.1038/s41586-022-05675-0 |
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