Direct observation of the conformational states of PIEZO1

PIEZOs are mechanosensitive ion channels that convert force into chemoelectric signals(1,2) and have essential roles in diverse physiological settings(3). In vitro studies have proposed that PIEZO channels transduce mechanical force through the deformation of extensive blades of transmembrane domain...

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Detalles Bibliográficos
Autores principales: Mulhall, Eric M., Gharpure, Anant, Lee, Rachel M., Dubin, Adrienne E., Aaron, Jesse S., Marshall, Kara L., Spencer, Kathryn R., Reiche, Michael A., Henderson, Scott C., Chew, Teng-Leong, Patapoutian, Ardem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468401/
https://www.ncbi.nlm.nih.gov/pubmed/37587339
http://dx.doi.org/10.1038/s41586-023-06427-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468401/
https://www.ncbi.nlm.nih.gov/pubmed/37587339
http://dx.doi.org/10.1038/s41586-023-06427-4

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