Ataxia-Telangiectasia Mutated Is Involved in Autolysosome Formation

Ataxia-telangiectasia mutated (ATM), a master kinase of the DNA damage response (DDR), phosphorylates a multitude of substrates to activate signaling pathways after DNA double-strand breaks (DSBs). ATM inhibitors have been evaluated as anticancer drugs to potentiate the cytotoxicity of DNA damage-ba...

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Detalles Bibliográficos
Autores principales: Hwang, Mihwa, Jun, Dong Wha, Song, Bo Ram, Shim, Hanna, Lee, Chang-Hun, Kim, Sunshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468418/
https://www.ncbi.nlm.nih.gov/pubmed/36941082
http://dx.doi.org/10.4062/biomolther.2023.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468418/
https://www.ncbi.nlm.nih.gov/pubmed/36941082
http://dx.doi.org/10.4062/biomolther.2023.003

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