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Niclosamide Inhibits Aortic Valve Interstitial Cell Calcification by Interfering with the GSK-3β/β-Catenin Signaling Pathway

The most common heart valve disorder is calcific aortic valve stenosis (CAVS), which is characterized by a narrowing of the aortic valve. Treatment with the drug molecule, in addition to surgical and transcatheter valve replacement, is the primary focus of researchers in this field. The purpose of t...

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Detalles Bibliográficos
Autores principales: Adhikari, Radhika, Shiwakoti, Saugat, Kim, Eunmin, Choi, Ik Jun, Park, Sin-Hee, Ko, Ju-Young, Chang, Kiyuk, Oak, Min-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468423/
https://www.ncbi.nlm.nih.gov/pubmed/37366053
http://dx.doi.org/10.4062/biomolther.2022.146