First-in-human study of a novel cell death tracer [(99m)Tc]Tc-Duramycin: safety, biodistribution and radiation dosimetry in healthy volunteers

BACKGROUND: Imaging of cell death can provide an early indication of treatment response in cancer. [(99m)Tc]Tc-Duramycin is a small-peptide SPECT tracer that recognizes both apoptotic and necrotic cells by binding to phosphatidylethanolamine present in the cell membrane. Preclinically, this tracer h...

Descripción completa

Detalles Bibliográficos
Autores principales: Metelerkamp Cappenberg, Taco, De Schepper, Stijn, Vangestel, Christel, De Lombaerde, Stef, wyffels, Leonie, Van den Wyngaert, Tim, Mattis, Jeffrey, Gray, Brian, Pak, Koon, Stroobants, Sigrid, Elvas, Filipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468453/
https://www.ncbi.nlm.nih.gov/pubmed/37646865
http://dx.doi.org/10.1186/s41181-023-00207-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468453/
https://www.ncbi.nlm.nih.gov/pubmed/37646865
http://dx.doi.org/10.1186/s41181-023-00207-1

Ejemplares similares