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Using a synthetic machinery to improve carbon yield with acetylphosphate as the core
In microbial cell factory, CO(2) release during acetyl-CoA production from pyruvate significantly decreases the carbon atom economy. Here, we construct and optimize a synthetic carbon conserving pathway named as Sedoheptulose-1,7-bisphosphatase Cycle with Trifunctional PhosphoKetolase (SCTPK) in Esc...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468489/ https://www.ncbi.nlm.nih.gov/pubmed/37648707 http://dx.doi.org/10.1038/s41467-023-41135-7 |