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Using a synthetic machinery to improve carbon yield with acetylphosphate as the core

In microbial cell factory, CO(2) release during acetyl-CoA production from pyruvate significantly decreases the carbon atom economy. Here, we construct and optimize a synthetic carbon conserving pathway named as Sedoheptulose-1,7-bisphosphatase Cycle with Trifunctional PhosphoKetolase (SCTPK) in Esc...

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Detalles Bibliográficos
Autores principales: Guo, Likun, Liu, Min, Bi, Yujia, Qi, Qingsheng, Xian, Mo, Zhao, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468489/
https://www.ncbi.nlm.nih.gov/pubmed/37648707
http://dx.doi.org/10.1038/s41467-023-41135-7