Benchmarking of force fields to characterize the intrinsically disordered R2-FUS-LC region

Intrinsically Disordered Proteins (IDPs) play crucial roles in numerous diseases like Alzheimer's and ALS by forming irreversible amyloid fibrils. The effectiveness of force fields (FFs) developed for globular proteins and their modified versions for IDPs varies depending on the specific protei...

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Detalles Bibliográficos
Autores principales: Chan-Yao-Chong, Maud, Chan, Justin, Kono, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468508/
https://www.ncbi.nlm.nih.gov/pubmed/37648703
http://dx.doi.org/10.1038/s41598-023-40801-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468508/
https://www.ncbi.nlm.nih.gov/pubmed/37648703
http://dx.doi.org/10.1038/s41598-023-40801-6

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