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Benchmarking of force fields to characterize the intrinsically disordered R2-FUS-LC region
Intrinsically Disordered Proteins (IDPs) play crucial roles in numerous diseases like Alzheimer's and ALS by forming irreversible amyloid fibrils. The effectiveness of force fields (FFs) developed for globular proteins and their modified versions for IDPs varies depending on the specific protei...
Autores principales: | Chan-Yao-Chong, Maud, Chan, Justin, Kono, Hidetoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468508/ https://www.ncbi.nlm.nih.gov/pubmed/37648703 http://dx.doi.org/10.1038/s41598-023-40801-6 |
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