A Fluorescent Probe as a Lead Compound for a Selective α-Synuclein PET Tracer: Development of a Library of 2-Styrylbenzothiazoles and Biological Evaluation of [(18)F]PFSB and [(18)F]MFSB

[Image: see text] A method to detect and quantify aggregated α-synuclein (αSYN) fibrils in vivo would drastically impact the current understanding of multiple neurodegenerative diseases, revolutionizing their diagnosis and treatment. Several efforts have produced promising scaffolds, but a notable c...

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Detalles Bibliográficos
Autores principales: Di Nanni, Adriana, Saw, Ran Sing, Battisti, Umberto M., Bowden, Gregory D., Boeckermann, Adam, Bjerregaard-Andersen, Kaare, Pichler, Bernd J., Herfert, Kristina, Herth, Matthias M., Maurer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468942/
https://www.ncbi.nlm.nih.gov/pubmed/37663501
http://dx.doi.org/10.1021/acsomega.3c04292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10468942/
https://www.ncbi.nlm.nih.gov/pubmed/37663501
http://dx.doi.org/10.1021/acsomega.3c04292

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