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Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution

Glucocorticoids (GC) are potent anti-inflammatory agents, broadly used to treat acute and chronic inflammatory diseases, e.g., critically ill COVID-19 patients or patients with chronic inflammatory bowel diseases. GC not only limit inflammation but also promote its resolution although the underlying...

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Detalles Bibliográficos
Autores principales: Rao, Zhigang, Brunner, Elena, Giszas, Benjamin, Iyer-Bierhoff, Aishwarya, Gerstmeier, Jana, Börner, Friedemann, Jordan, Paul M., Pace, Simona, Meyer, Katharina P. L., Hofstetter, Robert K., Merk, Daniel, Paulenz, Christian, Heinzel, Thorsten, Grunert, Philip C., Stallmach, Andreas, Serhan, Charles N., Werner, Markus, Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469032/
https://www.ncbi.nlm.nih.gov/pubmed/37603745
http://dx.doi.org/10.1073/pnas.2302070120