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scDemultiplex: An iterative beta-binomial model-based method for accurate demultiplexing with hashtag oligos

Single-cell sequencing have been widely used to characterize cellular heterogeneity. Sample multiplexing where multiple samples are pooled together for single-cell experiments, attracts wide attention due to its benefits of increasing capacity, reducing costs, and minimizing batch effects. To analyz...

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Detalles Bibliográficos
Autores principales: Huang, Li-Ching, Stolze, Lindsey K., Chen, Hua-Chang, Gelbard, Alexander, Shyr, Yu, Liu, Qi, Sheng, Quanhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469060/
https://www.ncbi.nlm.nih.gov/pubmed/37664174
http://dx.doi.org/10.1016/j.csbj.2023.08.013