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scDemultiplex: An iterative beta-binomial model-based method for accurate demultiplexing with hashtag oligos
Single-cell sequencing have been widely used to characterize cellular heterogeneity. Sample multiplexing where multiple samples are pooled together for single-cell experiments, attracts wide attention due to its benefits of increasing capacity, reducing costs, and minimizing batch effects. To analyz...
Autores principales: | Huang, Li-Ching, Stolze, Lindsey K., Chen, Hua-Chang, Gelbard, Alexander, Shyr, Yu, Liu, Qi, Sheng, Quanhu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469060/ https://www.ncbi.nlm.nih.gov/pubmed/37664174 http://dx.doi.org/10.1016/j.csbj.2023.08.013 |
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