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Selection of a novel cell-internalizing RNA aptamer specific for CD22 antigen in B cell acute lymphoblastic leukemia

Despite improvements in B cell acute lymphoblastic leukemia (B-ALL) treatment, a significant number of patients experience relapse of the disease, resulting in poor prognosis and high mortality. One of the drawbacks of current B-ALL treatments is the high toxicity associated with the non-specificity...

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Detalles Bibliográficos
Autores principales: Ruiz-Ciancio, Dario, Lin, Li-Hsien, Veeramani, Suresh, Barros, Maya N., Sanchez, Diego, Di Bartolo, Ary Lautaro, Masone, Diego, Giangrande, Paloma H., Mestre, María Belén, Thiel, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469072/
https://www.ncbi.nlm.nih.gov/pubmed/37662970
http://dx.doi.org/10.1016/j.omtn.2023.07.028