Cargando…

The transcriptomic landscape of normal and ineffective erythropoiesis at single-cell resolution

The anemias of myelodysplastic syndrome (MDS) and Diamond Blackfan anemia (DBA) are generally macrocytic and always reflect ineffective erythropoiesis yet result from diverse genetic mutations. To delineate shared mechanisms that lead to cell death, we studied the fate of single erythroid marrow cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Doty, Raymond T., Lausted, Christopher G., Munday, Adam D., Yang, Zhantao, Yan, Xiaowei, Meng, Changting, Tian, Qiang, Abkowitz, Janis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469080/
https://www.ncbi.nlm.nih.gov/pubmed/37352261
http://dx.doi.org/10.1182/bloodadvances.2023010382