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Binding and Avidity Signatures of Polyclonal Sera From Individuals With Different Exposure Histories to Severe Acute Respiratory Syndrome Coronavirus 2 Infection, Vaccination, and Omicron Breakthrough Infections

BACKGROUND: The number of exposures to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to vaccine antigens affect the magnitude and avidity of the polyclonal response. METHODS: We studied binding and avidity of different antibody isotypes to the spike, the receptor-binding domain (R...

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Detalles Bibliográficos
Autores principales: Singh, Gagandeep, Abbad, Anass, Tcheou, Johnstone, Mendu, Demodara Rao, Firpo-Betancourt, Adolfo, Gleason, Charles, Srivastava, Komal, Cordon-Cardo, Carlos, Simon, Viviana, Krammer, Florian, Carreño, Juan Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469125/
https://www.ncbi.nlm.nih.gov/pubmed/37104046
http://dx.doi.org/10.1093/infdis/jiad116