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The RNA binding proteins TIA1 and TIAL1 promote Mcl1 mRNA translation to protect germinal center responses from apoptosis

Germinal centers (GCs) are essential for the establishment of long-lasting antibody responses. GC B cells rely on post-transcriptional RNA mechanisms to translate activation-associated transcriptional programs into functional changes in the cell proteome. However, the critical proteins driving these...

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Detalles Bibliográficos
Autores principales: Osma-Garcia, Ines C., Mouysset, Mailys, Capitan-Sobrino, Dunja, Aubert, Yann, Turner, Martin, Diaz-Muñoz, Manuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469172/
https://www.ncbi.nlm.nih.gov/pubmed/37474714
http://dx.doi.org/10.1038/s41423-023-01063-4