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Design of an alternate antibody fragment format that can be produced in the cytoplasm of Escherichia coli

With increased accessibility and tissue penetration, smaller antibody formats such as antibody fragments (Fab) and single chain variable fragments (scFv) show potential as effective and low-cost choices to full-length antibodies. These formats derived from the modular architecture of antibodies coul...

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Detalles Bibliográficos
Autores principales: Tungekar, Aatir A., Ruddock, Lloyd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469194/
https://www.ncbi.nlm.nih.gov/pubmed/37648872
http://dx.doi.org/10.1038/s41598-023-41525-3