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Design of an alternate antibody fragment format that can be produced in the cytoplasm of Escherichia coli
With increased accessibility and tissue penetration, smaller antibody formats such as antibody fragments (Fab) and single chain variable fragments (scFv) show potential as effective and low-cost choices to full-length antibodies. These formats derived from the modular architecture of antibodies coul...
Autores principales: | Tungekar, Aatir A., Ruddock, Lloyd W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469194/ https://www.ncbi.nlm.nih.gov/pubmed/37648872 http://dx.doi.org/10.1038/s41598-023-41525-3 |
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