Leverage of nuclease-deficient CasX for preventing pathological angiogenesis

Gene editing with a CRISPR/Cas system is a novel potential strategy for treating human diseases. Pharmacological inhibition of phosphoinositide 3-kinase (PI3K) δ suppresses retinal angiogenesis in a mouse model of oxygen-induced retinopathy. Here we show that an innovative system of adeno-associated...

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Detalles Bibliográficos
Autores principales: Han, Haote, Yang, Yanhui, Jiao, Yunjuan, Qi, Hui, Han, Zhuo, Wang, Luping, Dong, Lijun, Tian, Jingkui, Vanhaesebroeck, Bart, Li, Xiaopeng, Liu, Junwen, Ma, Gaoen, Lei, Hetian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469388/
https://www.ncbi.nlm.nih.gov/pubmed/37662968
http://dx.doi.org/10.1016/j.omtn.2023.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469388/
https://www.ncbi.nlm.nih.gov/pubmed/37662968
http://dx.doi.org/10.1016/j.omtn.2023.08.001

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