ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC

BACKGROUND & AIMS: Phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme of the de novo serine synthesis pathway (SSP), has been implicated in the carcinogenesis and metastasis of hepatocellular carcinoma (HCC) because of its excessive expression and promotion of SSP. In previous expe...

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Detalles Bibliográficos
Autores principales: Wang, Huihui, Lin, Furong, Xu, Zhenzhen, Yu, Shengnan, Li, Guannan, Liao, Shan, Zhao, Wentao, Zhang, Fengqiong, Wang, Jinyang, Wang, Shijie, Ouyang, Cong, Zhang, Cixiong, Xia, Hailong, Wu, Yufei, Jiang, Bin, Li, Qinxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469392/
https://www.ncbi.nlm.nih.gov/pubmed/37331567
http://dx.doi.org/10.1016/j.jcmgh.2023.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469392/
https://www.ncbi.nlm.nih.gov/pubmed/37331567
http://dx.doi.org/10.1016/j.jcmgh.2023.06.006

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