Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

BACKGROUND: Amyloid-related imaging abnormalities (ARIA) have been identified as the most common and serious adverse events resulting from pathological changes in the cerebral vasculature during several recent anti-amyloid-β (Aβ) immunotherapy trials. However, the precise cellular and molecular mech...

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Detalles Bibliográficos
Autores principales: Taylor, Xavier, Clark, Isaiah M., Fitzgerald, Griffin J., Oluoch, Herold, Hole, Justin T., DeMattos, Ronald B., Wang, Yaming, Pan, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469415/
https://www.ncbi.nlm.nih.gov/pubmed/37649100
http://dx.doi.org/10.1186/s13024-023-00649-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469415/
https://www.ncbi.nlm.nih.gov/pubmed/37649100
http://dx.doi.org/10.1186/s13024-023-00649-w

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