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Mammalian display to secretion switchable libraries for antibody preselection and high throughput functional screening

Recently, there has been a co-evolution of mammalian libraries and diverse microfluidic approaches for therapeutic antibody hit discovery. Mammalian libraries enable the preservation of full immune repertoires, produce hit candidates in final format and facilitate broad combinatorial bispecific anti...

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Detalles Bibliográficos
Autores principales: Gaa, Ramona, Mayer, Hannah Melina, Noack, Daniela, Kumari, Kavita, Guenther, Ralf, Tsai, Shang-Pu, Ji, Qingyong, Doerner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469430/
https://www.ncbi.nlm.nih.gov/pubmed/37646089
http://dx.doi.org/10.1080/19420862.2023.2251190