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Mammalian display to secretion switchable libraries for antibody preselection and high throughput functional screening
Recently, there has been a co-evolution of mammalian libraries and diverse microfluidic approaches for therapeutic antibody hit discovery. Mammalian libraries enable the preservation of full immune repertoires, produce hit candidates in final format and facilitate broad combinatorial bispecific anti...
Autores principales: | Gaa, Ramona, Mayer, Hannah Melina, Noack, Daniela, Kumari, Kavita, Guenther, Ralf, Tsai, Shang-Pu, Ji, Qingyong, Doerner, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469430/ https://www.ncbi.nlm.nih.gov/pubmed/37646089 http://dx.doi.org/10.1080/19420862.2023.2251190 |
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