scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis

BACKGROUND: Here we present scSNPdemux, a sample demultiplexing pipeline for single-cell RNA sequencing data using natural genetic variations in humans. The pipeline requires alignment files from Cell Ranger (10× Genomics), a population SNP database and genotyped single nucleotide polymorphisms (SNP...

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Detalles Bibliográficos
Autores principales: Wong, John K. L., Jassowicz, Lena, Herold-Mende, Christel, Seiffert, Martina, Mallm, Jan-Philipp, Lichter, Peter, Zapatka, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469441/
https://www.ncbi.nlm.nih.gov/pubmed/37653401
http://dx.doi.org/10.1186/s12859-023-05440-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469441/
https://www.ncbi.nlm.nih.gov/pubmed/37653401
http://dx.doi.org/10.1186/s12859-023-05440-8

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