Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice

Hepatic ischemia/reperfusion injury (IRI) often causes serious complications in liver surgeries, including transplantation. Complement activation seems to be involved in hepatic IRI; however, no complement-targeted intervention has been clinically applied. We investigated the therapeutic potential o...

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Detalles Bibliográficos
Autores principales: Kusakabe, Jiro, Hata, Koichiro, Tajima, Tetsuya, Miyauchi, Hidetaka, Zhao, Xiangdong, Kageyama, Shoichi, Tsuruyama, Tatsuaki, Hatano, Etsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469474/
https://www.ncbi.nlm.nih.gov/pubmed/37662914
http://dx.doi.org/10.3389/fimmu.2023.1174243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469474/
https://www.ncbi.nlm.nih.gov/pubmed/37662914
http://dx.doi.org/10.3389/fimmu.2023.1174243

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