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Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice
Hepatic ischemia/reperfusion injury (IRI) often causes serious complications in liver surgeries, including transplantation. Complement activation seems to be involved in hepatic IRI; however, no complement-targeted intervention has been clinically applied. We investigated the therapeutic potential o...
Autores principales: | Kusakabe, Jiro, Hata, Koichiro, Tajima, Tetsuya, Miyauchi, Hidetaka, Zhao, Xiangdong, Kageyama, Shoichi, Tsuruyama, Tatsuaki, Hatano, Etsuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469474/ https://www.ncbi.nlm.nih.gov/pubmed/37662914 http://dx.doi.org/10.3389/fimmu.2023.1174243 |
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