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Serum concentration of antigen-specific IgG can substantially bias interpretation of antibody-dependent phagocytosis assay readout

Because virus neutralization cannot solely explain vaccine-induced, antibody-mediated protection, antibody effector functions are being considered as a potential correlate of protection (CoP). However, measuring effector functions at a fixed serum dilution for high throughput purposes makes it diffi...

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Detalles Bibliográficos
Autores principales: St. Germain, Russell, Bossard, Emily L., Corey, Lawrence, Sholukh, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469534/
https://www.ncbi.nlm.nih.gov/pubmed/37664583
http://dx.doi.org/10.1016/j.isci.2023.107527