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Serum concentration of antigen-specific IgG can substantially bias interpretation of antibody-dependent phagocytosis assay readout
Because virus neutralization cannot solely explain vaccine-induced, antibody-mediated protection, antibody effector functions are being considered as a potential correlate of protection (CoP). However, measuring effector functions at a fixed serum dilution for high throughput purposes makes it diffi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469534/ https://www.ncbi.nlm.nih.gov/pubmed/37664583 http://dx.doi.org/10.1016/j.isci.2023.107527 |