Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development

Acute myeloid leukemia (AML) is an aggressive blood cancer that stems from the rapid expansion of immature leukemic blasts in the bone marrow. Mutations in epigenetic factors represent the largest category of genetic drivers of AML. The chromatin assembly factor CHAF1B is a master epigenetic regulat...

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Detalles Bibliográficos
Autores principales: Dean, Sarai T., Ishikawa, Chiharu, Zhu, Xiaoqin, Walulik, Sean, Nixon, Timothy, Jordan, Jessica K., Henderson, Samantha, Wyder, Michael, Salomonis, Nathan, Wunderlich, Mark, Greis, Kenneth D., Starczynowski, Daniel T., Volk, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469560/
https://www.ncbi.nlm.nih.gov/pubmed/37205848
http://dx.doi.org/10.1182/bloodadvances.2022009438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10469560/
https://www.ncbi.nlm.nih.gov/pubmed/37205848
http://dx.doi.org/10.1182/bloodadvances.2022009438

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